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Comparative analyses of carbamylation and citrullination in relation to rheumatoid arthritis and periodontitis and their changes after periodontal treatment.

Comparative analyses of carbamylation and citrullination in relation to rheumatoid arthritis and periodontitis and their changes after periodontal treatment. - Comparative analyses of carbamylation and citrullination in relation to rheumatoid arthritis and periodontitis and their changes after periodontal treatment.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030541
Enrollment
50
Registered
2017-12-25
Start date
2017-12-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis and periodontitis

Interventions

Periodontal treatment

Sponsors

Niigata University Medical and Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with rheumatoid arthritis and periodontitis

Exclusion criteria

Exclusion criteria: Having less than 15 teeth, the presence of diabetes mellitus or pregnancy, history or the presence of any periodontal and antibiotic treatment within the previous 3 months.

Design outcomes

Primary

MeasureTime frame
Serum levels of carbamylated protein and NETs

Secondary

MeasureTime frame
Probing depth, clinical attachment level, DAS28-CRP

Countries

Japan

Contacts

Public ContactTetsuo Kobayashi

Niigata University Medical and Dental Hospital General Dentistry and Clinical Education Unit

kotetsuo@dent.niigata-u.ac.jp025-227-2870

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026