Patient with ulcerative colitis
Conditions
Interventions
None listed
Sponsors
Hamamatsu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with known ulcerative colitis Category A: outpatient, in clinical remission defined as the Rachmilewitz index of 0-4 points Category B: active inpatient 2. Written informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with dysphagia 2. Pregnant or possible pregnant women 3. Patients with a pacemaker or other implanted electromedical device 4. Patients with present or past history of small and large bowel obstruction 5. Patients with a contraindication to bowel preparation (congestive heart failure, renal insufficiency, a life-threatening condition) 6. Patients with an allergy to polyethylene glycol, magnesium citrate, sennoside, metoclopramide or mosapride citrate 7. Patients who will undergo MRI 2 weeks after CCE 8. Patients inappropriate for this study by other reasons judged by investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The rate of total colon observation within its battery life, and transit time 2. Severity of mucosal inflammation in clinical remission assessed by CCE using Mayo endoscopic subscore (Mayo ES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cleansing level with a 4-point grading scale (poor, fair, good, and excellent) 2. Adverse events 3. Relapse-free survival, Exacerbation-free survival, surgery-free survival 4. Acceptability of CCE assessed by questionnaire survey. | — |
Countries
Japan
Contacts
Public ContactSatoshi Osawa
Hamamatsu University School of Medicine Department of Endoscopic and Photodynamic Medicine
Outcome results
None listed