Prospective interventional study assessing the effectiveness on ameliorating surgical stress and the enhancement of recovery after surgery by Miyagi Cancer Center Head and Neck ERAS Protocol (MCC-HN ERAS)

Prospective interventional study assessing the effectiveness on ameliorating surgical stress and the enhancement of recovery after surgery by Miyagi Cancer Center Head and Neck ERAS Protocol (MCC-HN ERAS) - ERAS protocol for head and neck cancer at Miyagi Cancer Center (MCC-HN-ERAS)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030467

Enrollment

Registered

2017-12-19

Start date

2017-06-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Cancers

Interventions

Intervention with MCC-HN-ERAS protocol. 1) Preoperative administration of dexamethasone. 2) Preoperative oral rehydration. 3) Promotion of gastrointestinal peristalsis. 4) Stylization of pain ass

satisfaction rating (QoR-40 score). etc.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Head and neck cancer patients who receive the surgeries with primary resection and free tissue transfer reconstruction. 2) Patients with written informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with hypersensitivity to dexamethasone. 2) Patients with active infectious diseases such as tuberculosis, viral infection and mycosis. 3) Patients with thrombosis. 4) Patients with poor-controlled diabetes mellitus; e.g. insulin dependent. 5) Patients with uncontrolled psycogenic disease, such as depression. 6) Patients with active peptic ulcer. 7) Patients with uncontrolled glaucoma. 8) Patients with regular use of oral steroid for such conditions as autoimmune disease.

Design outcomes

Primary

Measure	Time frame
1)Postoperative period to discharge. 2)Postoperative period to the day meeting the discharge criteria.	—

Secondary

Measure	Time frame
1) Postoperative patients' satisfaction rating (QoR-40 score) 2) Inflammatory response as surgical invasiveness 3) Pain control 4) Postoperative nausea and vomiting 5) Postoperative period until the commencement of enteral nutrition 6) Nutritional intake independence 7) Daily activities independence 8) Water balance 9) Organ disorder 10) Postoperative complication 11) Protocol compliance rate	—

Countries

Japan

Contacts

Public ContactImai Takayuki

Miyagi Cancer Center Head and Neck Surgery

takayuki.imai629@gmail.com022-384-3151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026