Feasibility and effecacy of risk-reducing surgery for BRCA1/2 deleterious mutation carriers

Feasibility and effecacy of risk-reducing surgery for BRCA1/2 deleterious mutation carriers - Risk-reducing surgery for BRCA1/2 deleterious mutation carriers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030431

Enrollment

Registered

2017-12-18

Start date

2017-12-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer Ovarian cancer

Interventions

Risk-reducing salpingo-oophorectomy Risk-reducing mastectomy with breast reconstruction

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Carriers of deleterious mutation of BRCA1 or BRCA2

Exclusion criteria

Exclusion criteria: Non-carriers of deleterious mutation of BRCA1 or BRCA2 Patients who has not received genetic testing for BRCA1 or BRCA2 Carriers who dose not hope to receive risk-reducing surgery Carriers who dose not give her consent for risk-reducing surgery

Design outcomes

Primary

Measure	Time frame
frequency of surgical complications	—

Secondary

Measure	Time frame
Preventive efficacy of breast and ovarian cancer	—

Countries

Japan

Contacts

Public ContactYasuhiro Tamaki

Osaka International Cancer Institute Breast and endocrine surgery

tamaki-ya@mc.pref.osaka.jp06-6945-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026