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Japanese Multi-Center Study for Utility of 3D Computer-Aided Detection System at Lung Cancer Screening with Low-dose CT Protocol

Japanese Multi-Center Study for Utility of 3D Computer-Aided Detection System at Lung Cancer Screening with Low-dose CT Protocol - Japanese Multi-Center Trial of 3D CAD System and Low-Dose CT Protocol for Lung cancer Screening

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030415
Enrollment
600
Registered
2018-04-01
Start date
2019-02-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nodule

Interventions

Comparison of nodule detection capability among CAD alone and CAD with concurrent and second reading methods with physicians

Sponsors

Department of Radiology, Kobe University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Equal to or more than 40-years old 2. Written informed consent is obtained. 3. Patients with radiological, microbacterial, histological and laboratorial as well as more than two-years follow-up CT examinations are performed.

Exclusion criteria

Exclusion criteria: 1. Already included subject 2. Pregnant woman or female with possibility for pregnancy 3. Patients who undergo standard-dose CT examination and don't allow any further radiation exposure. 4. Patient who is considered as non inclusive by researchers

Design outcomes

Primary

MeasureTime frame
Results of compared nodule detection capability among CAD system alone and CAD system with concurrent and second reading method by physicians.

Secondary

MeasureTime frame
1. Comparison of quantitative image quality at various dose CTs among FBP, AIDR 3D and FIRST 2. Comparison of qualitative image quality at various dose CTs among FBP, AIDR 3D and FIRST 3. Comparison for nodule detection capability of CAD system among standard-, reduced- and ultra-low-dose CTs 4. Comparison for nodule detection capability at standard-, reduced- and ultra-low-dose CTs among CAD system alone and CAD system with concurrent and second reading methods by physicians

Countries

Japan

Contacts

Public ContactShinichiro Seki

Kobe University Hospital Department of Radiology

klfsiena@yahoo.co.jp+81-78-382-6104

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026