Healthy Volunteer
Conditions
Interventions
Placebo(single ingestion) - washout period - test food(single ingestion)
Test food(single ingestion) - washout period - Placebo(single ingestion)
Sponsors
Otsuka Pharmaceutical Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy males aged between 30 and 64. Healthy post-menopausal females aged between 50 and 64 with no menstruation in the past 12 months. 2)Subjects who 24hr Urinary sodium in screening examination is lower. 3)Subjects who routinely not take medicine, supplements, FOSHU, and/or health food which affect to the result of the study.
Exclusion criteria
Exclusion criteria: 1) Subjects who have allergy to medicinal and foods. 2) Subjects who has under treatment or a history of serious disease (e.g., diabetes, liver disease, kidney disease, or heart disease). 3) Subjects who systolic blood pressure is more than 140 mmHg or diastolic blood pressure is more than 90 mmHg. 4) Subjects who BMI is more than 30 kg/m2. 5) Subjects who make a blood donation of 400 ml within 12 weeks before the start of the intake or that of 200 ml within 4 weeks before the start of the intake. 6) Subjects who are estimated inappropriate to participate to this study by principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary electrolyte | — |
Countries
Japan
Contacts
Public ContactTsuneyuki Noda
Otsuka Pharmaceutical Co., Ltd. Saga Nutraceuticals Research Institute
Outcome results
None listed