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Prospective study on early diagnosis of Parkinson's disease in medical checkup examinees with non-motor symptoms

Prospective study on early diagnosis of Parkinson's disease in medical checkup examinees with non-motor symptoms - NaT-PROBE

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030396
Enrollment
60
Registered
2018-01-01
Start date
2018-03-31
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#39

Interventions

Skin biopsy, MIBG scintigraphy and DaT scan

Sponsors

Nagoya University, Department of Neurology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Examinees of medical checkups who answered the questionnaire about non-motor symptoms of Parkinson disease Subjects who can make a outpatient visit regularly Subjects who agreed to participate in this study Subjects who fulfill one of the following criteria 1) participants who have two or more non-motor symptoms: SCOPAAUT, 10 or more; SAOQ, 90 or less; RBDSQ, 5 or more. 2) participants who don't have any non-motor symptoms: SCOPA-AUT, SAOQ, and RBDSQ scores are all normal.

Exclusion criteria

Exclusion criteria: Subjects who have mental and neurological disorders other than depression Subjects who are inappropriate to participate in the study

Design outcomes

Primary

MeasureTime frame
Incidence of Parkinson's disease during the 10 year follow-up period—

Secondary

MeasureTime frame
Changes in H/M ratio of MIBG scintigraphy during the 10 year follow-up period Changes in SBR of DaT scan during the 10 year follow-up period—

Countries

Japan

Contacts

Public ContactKeita Hiraga

Nagoya University Graduate School of Medicine Department of Neurology

hiraga.keita.n5@f.mail.nagoya-u.ac.jp052-744-2391

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026