Kidney Neoplasm
Conditions
Interventions
After induction of anesthesia and before clamping of the renal artery, we perform remote ischemic preconditioning consisting of 3 cycles of 5-minute inflation of a blood pressure cuff to 200 mmHg to o
Sponsors
Tokyo Women's Medical University
Fukushima Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients with estimated glomerular filtration rate >= 30 mL/min/1.73m2 who give written informed consent and are scheduled to undergo open or robot-assisted laparoscopic partial nephrectomy for the renal mass with diameter >= 40 mm or RENAL nephrometry score >= 10.
Exclusion criteria
Exclusion criteria: 1. No limbs 2. Peripheral vascular disease affecting lower limbs 3. Peripheral nerve injury affecting lower limbs 4. Bleeding tendency 5. Cognitive disorder 6. Mental disorder requiring treatment 7. Poorly controlled diabetes (HbA1c >= 7.0%) 8. Drug therapy with sulfonamide or nicorandil 9. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The nadir estimated glomerular filtration rate (mL/min/1.73m2) within 7 days of operation | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of acute kidney injury; Estimated glomerular filtration rate (mL/min/1.73m2) at 1, 3 and 6 months after operation; Operation time; Ischemic time; Estimated blood loss; Adverse events | — |
Countries
Japan
Contacts
Public ContactKenji Omae
Tokyo Women's Medical University Department of Urology
Outcome results
None listed