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Risk factors of recurarization after insufficient sugammadex administration: Effects of obesity and obstructive sleep apnea

Risk factors of recurarization after insufficient sugammadex administration: Effects of obesity and obstructive sleep apnea - Effects of obesity and obstructive sleep apnea on recurarization following insufficient sugammadex

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030263
Enrollment
40
Registered
2017-12-05
Start date
2017-12-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with obesity, patients with obstructive sleep apnea, patients undergoing elective surgery

Interventions

infusion of insufficient sugammadex

Sponsors

Chiba University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: elective surgical patients under general anesthesia: 20 non-obese patients (BMI less than 25kg/m2) and 20 obese patients (BMI greater than 30 kg/m2)

Exclusion criteria

Exclusion criteria: Exclusion criteria were 1) patients with severe comorbidities, 2) allergies for muscle relaxants, propofol and sugammadex, 3) patients undergoing surgeries undesirable for administration of rocuronium and sugammadex, and 4) patients taking drugs that influence rocuronium and sugammadex such as antiepileptic agents, estrogen preparation, rifampicin and verapamil, 5) patients who the researcher judged inappropriate as the subject

Design outcomes

Primary

MeasureTime frame
TOF ratio recovery speed

Secondary

MeasureTime frame
Variables obtained from the neuromuscular monitoring, background variables

Countries

Japan

Contacts

Public ContactTakahiro Muramatsu

Chiba University Department of Anesthesiology, Graduate School of Medicine

rudy_sippo@yahoo.co.jp+81-43-226-2155

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026