Rectal cancer
Conditions
Interventions
Evaluation of blood flow by near infrared imaging using indocyanine green
control
Sponsors
Sapporo Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are histologically proven to be rectal cancer 2. The lower edge of the tumor is within 12 cm from the anal margin 3. Patients diagnosed with Stage 0-3 in preoperative diagnostic imaging 4. Patients who are scheduled for rectal resection with intestinal anastomosis (including ISR) 5. Patients with General State Performance Status (ECOG) 0 to 2 6. Patients whose age at registration is 20 years or older 7. Patients whose functions of the main organs are adequately maintained and judged to be safe for surgery by the doctor in charge of examination 1 White blood cell count> 3,000 / mm 3 2 platelet> 100,000 / mm 3 3 GOT <100 IU / L 4 GPT <100 IU / L 5 Total bilirubin <2.0 mg / dl 6 Cr <2.0 mg / dl 8. About participation in this study Patients who have obtained consent from a document stating signature and date by the applicant
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to iodine or indocyanine green 2. Preoperative intestinal obstruction patients 3. Patients planning simultaneous resection of other organs due to double cancer 4. Patients scheduled to anastomosis at more than two sites due to multiple colon cancer 5. Patients with intraperitoneal infection (peritonitis or abdominal abscess) 6. Patients with serious complications (heart disease, lung disease, bleeding tendency, poorly controlled hypertension, diabetes etc.) 7. Pregnancy and patients with fear thereof 8. Other patients judged inappropriate by the examining physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anastomotic leakage rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Anastomotic leakage rate(Grade B+C) Fluorescence time at the oral side anastomotic site Rate of the additional transection of the proximal colon toward the oral side Length of the additional transection of the proximal colon toward the oral side Rates of complications within 30 days after surgery Rates of complications during surgery Reoperation rate Postoperative hospital stay | — |
Countries
Japan
Contacts
Public ContactJun Watanabe
Yokohama City University Medical Center Department of surgery
Outcome results
None listed