febrile status epilepticus
Conditions
Interventions
Patient filling inclution criteria are started on Dextromethrophan 2mg/kg/day within 6hours after status epilepticus for 5 days.
Sponsors
Tokyo Medical and Dental University Department of Pediatrics
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The subjects are patients who meet following three inclusion criteria 1) Patients who are 6 months of age more but less than 3 years of age 2) Patients with status epilepticus(patients have convulsion more than 15 minutes) 3)Patients whose convulsion could not been stoped quickly using the first choise therapy(diazepam or midazoram) and the second choise therapy(phenytoin)(However, in regard to using continuous idazoram infusion, the case using as a second choise and failing to stop convulsion meets criteria)
Exclusion criteria
Exclusion criteria: The sujects are patients who meet following five exclusion criteria 1) Patients who are clearly suspitious of intracranial infection, cranial tumor and intracranial vascular lesion 2) patients who are clearly cranial hemorrhage for head MRI and CT in 1 or 2 days after occuring status epilepticus 3) Patients Who are acute necrotizing encephalopathy 4) Patients who already take antiepileptic drugs against epilepsy 5) Patients who already take dextromethrophan against upper respiratory infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome are occuring second seizures and consiousness disorder in 3-7 days after first seizure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are age(between six months and one year versus between one and three years), sex, duration of seizure(less than 45 minutes versus more than 45 minutes), past history(whether patients experience feblire seizure or not), and value of AST and blood suger at admission. | — |
Countries
Japan
Contacts
Public ContactKengo Moriyama
Tokyo Medical and Dental University Department of Pediatrics
Outcome results
None listed