Effect of Bifidobacterium consumption on IgA production in low birth weight infant

Effect of Bifidobacterium consumption on IgA production in low birth weight infant - Study of Bifidobacterium consumption in low birth weight infant

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030213

Enrollment

Registered

2019-03-31

Start date

2016-08-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low birth weight infant

Interventions

Infant formula during hospitalization: Infant formula for low-birth weight infant added Bifidobacterium bifidum OLB6378 Infant formula after leaving hospital: Infant formula for term infant added B

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.infant whose birth weight: 1500g to 2500g 2.Infant who parents consent is obtained

Exclusion criteria

Exclusion criteria: 1. severe bacterila infection 2. congenital anomaly 3. hospitalization more than 2 months 4. not suitabel for the trial defined by the attending neonatologist

Design outcomes

Primary

Measure	Time frame
Fecal IgA (1 month to 18 month age)	—

Secondary

Measure	Time frame
salivary IgA, IgA/protein, salivary secretory component, secretory component/protein, serum TGF, IL-10, IgE, Specific IgE, allergy symptoms, during 1 month to 18 month age	—

Countries

Japan

Contacts

Public ContactOuki Furukawa

Shiga University of Medical Science Department of Pediatrics

ouki@belle.shiga-med.ac.jp077-548-2553

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026