Early glottis cancer
Conditions
Interventions
(Interventions) Patients who receive carotid-sparing (max dose<
35Gy) intensity-modulated radiotherapy in early glottis cancer
(Control) Patients with head and neck cancer who receive radiotherapy (more than 50Gy) without carotid-saprinig
Sponsors
Juntendo University, Graduate School of Medicine, Department of Radiation Oncology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (Interventions) Patients with glottis cancer who meet all of the following criteria; 1.Clinical T1 or T2 (UICC ver.7) glottis cancer diagnosed by laryngeal endoscope and CT or MRI 2.Pathologically confirmed squamous cell cancer 3.Clinical N0 and M0 diagnosed by neck CT and chest Xp (chest CT) 4.Age over 20 5.Performance status (ECOG) 0-2 6.No prior surgery or radiotherapy against neck 7.Written informed consent (Control) Patients with head and neck cancer who meet all of the following criteria; 1.Age over 20 2.Pathologically confirmed head and neck cancer 3.Will receive radiotherapy more than 50Gy 4.Performance status (ECOG) 0-2 5.Written informed consent
Exclusion criteria
Exclusion criteria: (Interventions/control) 1.Patients have psychiatric disorders that may comprise the patient's ability to receive radiotherapy 2.Patients who is considered ineligible for enrolling the study by a principal investigator or sub-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid intima-media thickness after radiotherapy 1,2 years later | — |
Secondary
| Measure | Time frame |
|---|---|
| Local control rate after radiotherapy 1,2 years later | — |
Countries
Japan
Contacts
Public ContactKosugi Yasuo
Juntendo University Department of Radiation Oncology
Outcome results
None listed