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Intermittent versus continuous local anesthetics administration in postoperative paravertebral block for patients undergoing video assisted thoracic surgery: a double blinded randomized controlled trial

Intermittent versus continuous local anesthetics administration in postoperative paravertebral block for patients undergoing video assisted thoracic surgery: a double blinded randomized controlled trial - Intermittent versus continuous local anesthetics administration in postoperative paravertebral block for patients undergoing video assisted thoracic surgery: a double blinded randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030174
Enrollment
60
Registered
2017-12-01
Start date
2018-01-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases which need video assisted thoracic surgery under general anesthesia

Interventions

Bolus administration of 15mL local anesthetics is repeated every 3 hours for up to 48 hours after surgery. Local anesthetics administered continuously at a rate of 5 mL/h for up to 48 hours after surg

Sponsors

Dept. of Anesthesiology, Wakayama Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients over 20 years old who will undergo video assisted thoracic surgery with postoperative paravertebral block

Exclusion criteria

Exclusion criteria: 1. Patients who will undergo emergency surgery 2. Patients whose serum free local anesthetic concentration can easily be increased. 3. Patients whose paravertebral catheter is difficult to be inserted or to be confirmed the right position. 4. Patients who are inappropriate to be administered contrast medium. 5. Patients who cannot be interviewed after surgery 6. Patients who have allergy to drugs included in the study 7. Patients who suffered from unexpected complications of the surgery or anesthesia 8. Patients who are planned to be sedated after surgery

Design outcomes

Primary

MeasureTime frame
Cumulative dose of local anesthetics during postoperative 48 hours

Secondary

MeasureTime frame
1) Mean score of visual analogue scale (VAS) for pain during postoperative 6 hours 2) Satisfaction scores on VAS for postoperative 24 hours 3) Percentage of the patients showed signs or symptoms of local anesthetic toxicity

Countries

Japan

Contacts

Public ContactKeisuke Fujii

Wakayama Medical University Dept. of Anesthesiology

fujiik@wakayama-med.ac.jp073-441-0611

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026