Effects of grape seed proanthocyanidin extract on the endothelial function in patients with stage 1 hypertension

Effects of grape seed proanthocyanidin extract on the endothelial function in patients with stage 1 hypertension - Effects of grape seed proanthocyanidin extract on the endothelial function in patients with stage 1 hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030171

Enrollment

Registered

2017-11-29

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stage 1 hypertension

Interventions

12-week treatment with 400 mg of proantohocyanidin 12-week treatment with 200 mg of proantohocyanidin 12-week treatment with 0 mg of proantohocyanidin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 130 mmHg <= systolic pressure <140 mmHg and/or 85 mmHg <= diastolic pressure < 90 mmHg

Exclusion criteria

Exclusion criteria: patients who are being treated with antihypertensive drugs or dietary supplements proven to lower blood pressure

Design outcomes

Primary

Measure	Time frame
endothelial function after 12 weeks of treatment	—

Countries

Japan

Contacts

Public ContactMasakazu Terauchi

Tokyo Medical and Dental University Department of Women's Health

teragyne@tmd.ac.jp03-5803-4605

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026