Modification of Neurotransmission of Brain-Gut Interactions

Modification of Neurotransmission of Brain-Gut Interactions - Neuro-modification of Brain-Gut

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030147

Enrollment

240

Registered

2018-04-01

Start date

2010-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irritable bowel syndrome healthy controls

Interventions

saline intravenous administration one time CRH intravenous administration one time alpha-helical CRH intravenous administration one time ramosetron intravenous administration one time naloxon

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Rome III/IV Asymptomatic healthy individual

Exclusion criteria

Exclusion criteria: organic diseases psychiatric diseases

Design outcomes

Primary

Measure	Time frame
brain images of positron emission tomography (PET)	—

Secondary

Measure	Time frame
ordinate scale psychometric tests plasma/serum hormones	—

Countries

Japan

Contacts

Public ContactShin Fukudo, MD, PhD

Tohoku University Graduate School of Medicine Department of Behavioral Medicine

sfukudo@med.tohoku.ac.jp022-717-8162

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026