Acute upper respiratory tract inflammation
Conditions
Interventions
12 weeks, Placebo drink, once a day
12 weeks, Active drink, including green tea-derived components, once a day
12 weeks, Active drink, including green tea-derived components, three times a day
Sponsors
University of Shizuoka
(1) White Cross Nursing Home (2) Tokyo White Cross Hospital (3) Tokyo-Bannan-Hakkoen (4) Kao-Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) The male and female employees aged 20 or over but under 75 who work in medical and welfare facilities (2) Able to give written informed consent (3) Able to intake tea catechins (4) Able to write questionnaire
Exclusion criteria
Exclusion criteria: (1) Potentially having the allergy to tea-derived components (2) Having severe systemic chronic infectious diseases (3) Being difficulty to participate the study due to having severe hepatic/renal/ cardiac/respiratory/endocrinological/metabolic disorder, neurological and consciousness disorder, diabetes and other illnesses (4) Having severe immune deficiency or autoimmune disease, or taking drugs influencing immune functions (e.g. steroid, immunosuppressive drugs, and so on) (5) Not able to stop health products or supplements that potentially influence immune functions (6) Going to participate any clinical trial other than this study (7) Subjects diagnosed by physicians inappropriate to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence of acute upper respiratory tract inflammation (including influenza). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of influenza like illness. 2. Frequency of acute upper respiratory tract inflammation (including influenza). 3. Adverse events. | — |
Countries
Japan
Contacts
Public ContactHiroshi Yamada
University of Shizuoka School of Pharmaceutical Sciences
Outcome results
None listed