A randomized control trial of efficacy of endoscopic submucosal dissection using an ITknife nano for colorectal neoplasms larger than 30 mm in size

A randomized control trial of efficacy of endoscopic submucosal dissection using an ITknife nano for colorectal neoplasms larger than 30 mm in size - Device selection RCT in colorectal ESD (NANO STUDY)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030068

Enrollment

216

Registered

2017-12-01

Start date

2017-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal epitherial neoplasm

Interventions

Dual knife group ITknife nano group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who receive colorectal ESD 2) Colorectal epitherial neoplasms which are larger than 30 mm and smaller than 50 mm 3) Laterally spreading tumor (LST) 4) Written informed consent

Exclusion criteria

Exclusion criteria: 1) cT1b(SM) cancer 2) non-LST lesions 3) Local recurrences/ Scar lesions 4) Easy bleeding disorder 5) Impossible to suspend anticoagulant or antiplatelet medications 6) Women during pregnancy 7) Inappropriate cases by investigators

Design outcomes

Primary

Measure	Time frame
Procedure time	—

Countries

Japan

Contacts

Public ContactSayo Ito

Shizuoka Cancer Center Division of Endoscopy

sa.ito@scchr.jp055-989-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026