food allergy
Conditions
Interventions
soy milk oral food challenge (1-2-5-10-20 ml, 30 min interval) and partially hydrolyzed soy formula oral food challenge (2-4-10-20-40 ml, 30 min interval ) in the patient with soybean allergy
Sponsors
Aichi Children's Health and Medical Center
Department of Pediatrics, Fujita Health University Department of Nutrition Management, Nagoya University of Arts and Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patient with positive result for soy milk oral food challenge test(1-2-5-10-20 ml, 30 min interval)
Exclusion criteria
Exclusion criteria: patients during oral immunotherapy for other food antigen. patients with severe comorbidity. patients with uncontrollable asthma or atopic dermatitis. patients who have developed anaphylaxis by soy allergen within one year before the oral food challenge. patients whom the doctor asses ineligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The threshold dose of soy milk and partially hydrolyzed soy formula in the patient with soybean allergy | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy and safety at 6 months of oral immunotherapy using partially hydrolyzed soy formula. Change of the basophil activation by oral immunotherapy using partially hydrolyzed soy formula. IgE-immunoblotting and ELISA using the serum of the patients soybeans allegy. | — |
Countries
Japan
Contacts
Public ContactIwao Tajima
Aichi Children's Health and Medical Center Department of Allergy
Outcome results
None listed