Metastatic Epidural Spinal Cord Compression
Conditions
Interventions
Surgical decompression and postoperative stereotactic body radiotherapy of 24 Gy in 2 fractions.
Sponsors
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. pathological or clinical diagnosis of primary cancer (including sarcoma) 2. spine metastases confirmed by images 3. Symptoms by the tumor 4. Bilsky grade is more than Ib 5. Age; 20- 6. Other lesions are controlled, or the lesion was irradiated previously 7. prognosis is expected more than 6 months 8. Written informed consent
Exclusion criteria
Exclusion criteria: 1. Radiosensitive histology 2. the lesion was irradiated within 3 months 3. the lesion was treated with SBRT 4. untlerable to surgery 5. complete paralysis more than 48 hours 6. impossible to conduct decompression surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local control at 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Ambulatory function, OS, local progression free survival, pattern of failure, pain response, Adverse events, QOL | — |
Countries
Japan
Contacts
Public ContactKei Ito
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Division of Radiation Oncology, Department of Radiology
Outcome results
None listed