pharmacokinetics and pharmacodynamics study of intraveneous acetaminophen

pharmacokinetics and pharmacodynamics study of intraveneous acetaminophen - pharmacokinetics and pharmacodynamics study of intraveneous acetaminophen

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000030006

Enrollment

Registered

2017-11-20

Start date

2017-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who undergo head neck and oral surgery without nerve block or epidural anesthesia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA 1 and 2 Adult patient with good condition

Exclusion criteria

Exclusion criteria: 1.History of allergy to acetaminophen 2.History of aspirin asthma 3.Oral use of carbamazepine/phenobarbital/phenytoin/primidone/rifampicin 4.Psychoneurotic disorders 5.Psychiatric pharmacotherapy 6.Liver or advanced renal dysfunction 7.Alcohol drinkers and adddiction patient 8.Pregnant woman/breast-feeding 9.Those who were considered inadequate

Design outcomes

Primary

Measure	Time frame
Blood concentration of acetaminophen	—

Secondary

Measure	Time frame
VRS VAS NRS	—

Countries

Japan

Contacts

Public ContactTomoko Suzuki

Tohoku University Department of Anesthesiology and Perioperative Medicine

tomoko.suzuki.r2@dc.tohoku.ac.jp0227177321

Outcome results