Controlled study of the effects on glucose metabolism and gut microbiome by the treatment of sleep disorders

Controlled study of the effects on glucose metabolism and gut microbiome by the treatment of sleep disorders - correlation of sleep, glucose metabolism and gut microbiome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029999

Enrollment

Registered

2017-12-01

Start date

2017-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus, sleep disorders

Interventions

To analyse and compare gut microbime and glucose metabolism before and after 3months treatment by melatonin-receptor agonist(ramelteon) To analyse and compare gut microbime and glucose metabolism befo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with type 2 diabetes and sleep disorders

Exclusion criteria

Exclusion criteria: HbA1c<6.5% or >=10% severe liver dysfunction severe renal dysfunction(eGFR<30) previous cerebral infarction or myocardial infarction pregnant or breast-feeding hypersensitive to applicable drug judged as inappropriate by attending physician

Design outcomes

Primary

Measure	Time frame
The change of gut bacterial composition, increase or decrease of each bacterial phylum	—

Countries

Japan

Contacts

Public ContactShuhei Morita

Wakayama Medical University The First Department of Medicine

shuhei0528@gmail.com073-441-0625

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026