Perioperative Antioxidant enha nced Nutrition Effect on Liver S urgery

Perioperative Antioxidant enha nced Nutrition Effect on Liver S urgery - PANEL Study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029973

Enrollment

100

Registered

2017-11-15

Start date

2010-06-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver resection patients

Interventions

Enteral nutrition with antioxidant supplementation (600 kcal/d ay, ANOM (R)) are given 5 days preoperatively Normal enteral nutrition (600 k cal/day for 5 days preoperatively)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient undergoing liver resection including liver cirrhosis cases Over 18 years old Written informed consent is available

Exclusion criteria

Exclusion criteria: Without conditions as follows: Liver dysfunction like CHild-Pugh C or Liver damage C, Patients with hepatic coma, Patients with severe diabetes, ileus, gastroenteritis, short bowel syndrome, postgastrectomy status Congenital abnormalities in ami no acids metabolism Allergy in milk Allergy in ANOM(R) Pregnancy Responsuble physician diagnose d patients as inapropriate

Design outcomes

Primary

Measure	Time frame
Occurrence rate of infectious complications within 14 postoperative days	—

Secondary

Measure	Time frame
1) Changes in antioxidatic effect , 2) Improvement in liver function tests, 3) Changes in perioperative nutritional index, 4) Occurrence rate of infectious complications within 30 postoperative d ays, 5) Length of hospital stay, 6) Adverse effects	—

Countries

Japan

Contacts

Public ContactHIROYUKI SAKURAI

MIE UNIVERSITY MEDICAL AND NURSING EDUCATION CENTER

HIRODON@CLIN.MEDIC.MIE-U.AC.JP059-231-5654

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026