Temporomandibular disorders
Conditions
Interventions
Celecoxib group(fifty people administerd Celecoxib 100mg 2T/day for 14day)
Loxoprofen group(fifty people administerd Loxoprofen 60mg 3T/day and Mazuren Combination Tablete 1.0es 3T/day for 14day)
Sponsors
Saga University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patient diagnosed TMD 2)Patient aged from 15 to 70years old 3)Patient agreed this trial in writing
Exclusion criteria
Exclusion criteria: 1)Patient suffer from malignant tumor 2)Patient have medical history of hypersensivity to Sulfonamide and prescription drug 3)Patient have medical history of aspirin asthma 4)Patient suffer from peptic ulcer 5)Patient suffer from severe hepatopathy 6)Patient suffer from severe nephropathy 7)Patient suffer from blood disease 8)Patient suffer from cardiac function disturbance 9)Perioperative patient of coronary artery bypass operation 10)Patient take aspirin to prevent for cardiovascular disease 11)Patient have medical history of cardiovascular disease and cerebrovascular disorder 12)Last pregnanncy patient 13)Patient taken other anti-inframmatory analgesic 14)Patient who is judged inappropriate by doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain and Maximum mouth opening (with or without pain) assessed as of firstexamination,1week and 2week after administration | — |
Countries
Japan
Contacts
Public ContactKeisuke Mori
Saga University Hospital Department of oral and maxillofacial surgery
Outcome results
None listed