Cedar pollinosis
Conditions
Interventions
Take two capsules containing lactic acid bacteria a day
Take two placebo capsules a day
Sponsors
Department of Otolaryngology, Wakayama Medical University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Adult male and female from 20 to 60 years old (2) Subjects who can take capsules
Exclusion criteria
Exclusion criteria: (1) Subjects with symptoms of hay fever except cedar pollinosis at the stage of screening conducted from November 2017 to January 2018 (2) Subjects who regularly drink or eat live fungus-containing foods including lactic acid bacteria beverage, food,and preparation, and Bacillus natto (3) Subjects smorking (4) Pregnant women, lactating women, or women who want to get pregnant during the trial period (5)Subjects who show hypersensitivity symptoms to lactic acid bacteria foods (6) Subjects who investigator judge not suitable to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of s-IgA secreation | — |
Secondary
| Measure | Time frame |
|---|---|
| (1)Time course of s-IgA in saliva (2)Number of infections of influenza and viral emesis diarrhea (3)POMS 2 (mood profile test) (4)Stool frequency (5)Characteristics of stool (6)Organic acid in stool (7)Bacterial flora in stools The evaluation items below are done in the cedar pollinosis group (8)Specific IgE (cedar) concentration in blood (9)Nasal symptom score | — |
Countries
Japan
Contacts
Public ContactYuta Yamamoto
Wakayama Medical University School of Medicine Department of Anatomy and Cell Biology
Outcome results
None listed