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Development of a new biomarker for the detection of colorectal cancer using plasma concentrations of amino acids and metabolites

Development of a new biomarker for the detection of colorectal cancer using plasma concentrations of amino acids and metabolites - Biomarker Development for the detection of colorectal cancer using amino acids and metabolites

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000029920
Enrollment
400
Registered
2017-11-13
Start date
2017-11-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

None listed

Sponsors

Kyorin University School of Medicine The Third Department of Internal Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: A) Colorectal cancer patients (regardless of cancer stages). In Kyorin university, colorectal adenoma is also included. B) Age 25-90 C) People who agreed to the informed consent to participate in the study

Exclusion criteria

Exclusion criteria: A) Subjects who have taken any amino acid-formulations, supplements, and beverage within 8 hours before the blood collection. B) Subjects who have taken meals and beverage other than water within 8 hours before the blood collection. C) Subjects who are under medical treatment for any cancer including colorectal cancer (surgery, drug treatment, chemotherapy, radiation therapy) or who underwent surgery to remove cancer within 1 year. D) Subjects who have double cancer. E) Subjects who are pregnant or breast-feeding. F) Patients of inborn error of metabolism. G) Dialysis patients H) Subjects who are judged as ineligible by the medical doctors who are responsible for this trial as investigators.

Design outcomes

Primary

MeasureTime frame
Plasma concentrations of metabolites that have amino moieties and other metabolites

Secondary

MeasureTime frame
Fasting blood glucose, HbA1c Tumor markers (CEA, CA19-9 etc.) Stage of cancer Site of cancer Result of pathological examination Tissue type of cancer Tumor size Clinical parameters obtained in health chek-up

Countries

Japan

Contacts

Public ContactHidehiro Nakamura

Ajinomoto Co., Inc. Research Institute for Bioscience Products & Fine Chemicals

hidehiro_nakamura@ajinomoto.com044-210-5835

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026