Prospective intervention trial to evaluate the effectiveness of PPI for healing of ulcer after ESD

Prospective intervention trial to evaluate the effectiveness of PPI for healing of ulcer after ESD - Prospective intervention trial to evaluate the effectiveness of PPI for healing of ulcer after ESD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029919

Enrollment

160

Registered

2017-11-10

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancer

Interventions

Oral PPI for 8 weeks Do not take PPI for 8 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Patients with lesions whose resected area is expected to be less than three-fourths round 2 With regard to participation in this study, patients who gained document consent by their own voluntary intention

Exclusion criteria

Exclusion criteria: 1 Patients with lesions whose resection range is predicted to be more than three-fourths round 2 Patients who can not receive endoscopic examination for evaluating ulcer healing 3 Patients taking steroids before treatment 4 Patients who have taken PPI from before treatment and can not be discontinued

Design outcomes

Primary

Measure	Time frame
Presence or absence of healing of ulcer 4 weeks after esophagus ESD.	—

Secondary

Measure	Time frame
Presence or absence of healing of ulcer 8 weeks after esophagus ESD.	—

Countries

Japan

Contacts

Public ContactKoki Matsuoka

Kobe University Graduate School of Medicine Department of Endoscopy

mkouki@med.kobe-u.ac.jp078-382-5774

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026