A healthy adult
Conditions
Interventions
Intervention is 3 days. On each day, a subject intakes 180ml alcohol beverage of different 3 concentrations (0.01g/kg of body weight (BW), 0.1g/kg of BW, 0.3g/kg of BW or 0.5g/kg of BW ethanol) within
Sponsors
Yamaguchi University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?20<= years-old ?Male and Female ?A person who has ever drunken a unit of alcohol. ?A person who is standard weight (=>18.5 and <25) based on BMI (body mass index) ?A person who is provided sufficient explanations about this study and consented to it in writing by his own free will
Exclusion criteria
Exclusion criteria: ?a person who has ever had any allergy symptoms by drinking alcohol beverage ?a person who has any airway diseases or liver diseases ?a person who is probably pregnant or is during pregnancy ?a person who is during the lactation ?an inappropriate person for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in breath alcohol and acetaldehyde concentrations after drinking alcohol | — |
Secondary
| Measure | Time frame |
|---|---|
| Alcohol sensitivity by alcohol patch test and ADH1B/ALDH2 genotypes based on PCR method using oral mucosa. | — |
Countries
Japan
Contacts
Public ContactAyako Himemiya-Hakucho
Graduate School of Medicine, Yamaguchi University Department of Legal Medicine
Outcome results
None listed