Clinical study of low molecular Fish collagen peptide. A randomized, placebo-controlled double-blind study using low molecular fish collagen peptide in healthy adults suffering from occasional knee pain and discomfort -Verification of influence on knee joint function by continuous ingestion of low molecular fish collagen peptide-

Clinical study of low molecular Fish collagen peptide. A randomized, placebo-controlled double-blind study using low molecular fish collagen peptide in healthy adults suffering from occasional knee pain and discomfort -Verification of influence on knee joint function by continuous ingestion of low molecular fish collagen peptide- - Clinical study of low molecular Fish collagen peptide.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029871

Enrollment

Registered

2017-11-08

Start date

2017-11-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of low molecular weight of fish collagen peptide for 12 weeks. Ingestion of placebo for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The age, more than 45 years old, less than 75 years old, Healthy adult male and female. 2. A joint of the knee is uncomfortable feeling. But Medicine treatment isn't being performed. 3. The person who is giving written informed consent.

Exclusion criteria

Exclusion criteria: 1. The person is the knee arthritis and has a medical treatment by a doctor. The person diagnosed with osteoarthritis of the knee. 2. The person infected with cerebrovascular disease, a heart disease, a liver disease, a kidney disease and a digestive organ disease The person who judged that a trouble had the above medical history in clinical test participation 3. The person is allergy to medication and/or food. The person diagnosed with atopic dermatitis. 4. The person who had abnormality in the blood pressure and the laboratory test etc. in a screening. 5. The person who is taking healthy food and a supplement (hyaluronic acid, glucosamine etc.), and can't stop intake of these in the test duration. 6. The person who is started new medical treatment within 1week before intake the test food. The person who is plan to undergo medical treatment on knees during the study. 7. The person who judged that a test responsibility PI was disqualified.

Design outcomes

Primary

Measure	Time frame
VAS survey	—

Secondary

Measure	Time frame
VAS survey The knee joint function survey Life Style survey	—

Countries

Japan

Contacts

Public ContactDirector, Mikio Chibana,M.D.

OROKU HEART CLINIC N.A.

ren-ccrc@umin.ac.jp098-852-8080

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026