Dupuytren contracture
Conditions
Interventions
None listed
Sponsors
Nagoya University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient living in Japan who got written consent from this clinical study 1) Patients whose age is over 20 years 2) Dupuytran contracture of PIP (and MP) joint with palpable cord. One hand has two or more flexion contractures with more of which is Meyerding classification grade 2. Sex is not to be taken into question.
Exclusion criteria
Exclusion criteria: 1) Patients who had treated Dupuytran contracture in the past and recurred 2) Patients with a history of hypersensitivity to components of injectable collagenase 3) Patients who may be pregnant or pregnant, patients wishing for pregnancy during this clinical study or patients who may be pregnant, lactating patients 4) Patients who are receiving anticoagulant, antiplatelet drug (excluding aspirin at 150 mg / day or less) within 7 days before treatment 5) Patients who are separately participating in intervention tests such as trials and clinical trials 6) Patients who have difficulty understanding and answering inquiries of documents consent in Japanese, 7) Other Research Responsibilities (Sharing) Patients judged inappropriate for doctors to conduct this clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dupuytran contractures with palpable contracture cord were divided into two groups that were treated with collagenase injection or surgery (fasciectomy). The upper limb function before and after treatment is examined using a patient-rated outcome measure Hand10 as a primarily outcome. A cost utility analysis using direct cost and EQ-5D utility value is performed as secondary outcome. We will compare the injection group and surgery group. | — |
Countries
Japan
Contacts
Public ContactMichiro Yamamoto
Nagoya University Hand surgery
Outcome results
None listed