Randomized, double-blind study to evaluate the sensitivity and painfulness of different concentration of iodine solution during endoscopic examination to detect esophageal squamous epithelial tumor.

Randomized, double-blind study to evaluate the sensitivity and painfulness of different concentration of iodine solution during endoscopic examination to detect esophageal squamous epithelial tumor. - Randomized, double-blind study to evaluate the sensitivity and painfulness of different concentration of iodine solution during endoscopic examination to detect esophageal squamous epithelial tumor.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029796

Enrollment

Registered

2017-12-16

Start date

2017-12-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal squamous epithelial tumor

Interventions

different concentration of iodine solution(1%) different concentration of iodine solution(2%)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)The patients who have a superficial esophageal squamous cell carcinoma 2)A patient undergoing endoscopic examination after ESD for superficial esophageal cancer. 3)A past history of head and neck squamous cell cancer. 4)A patient who has more than six points in HRA-F score for esophageal cancer 5)A patient aged 20 years or older at the time of enrollment. 6)A patient who has provided written informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1) The patients treated by chemotherapy or radiotherapy and surgery for esophageal SCC or head and neck cancer. 2) A history of iodine hypersensitivity 3) A patient with sedative drugs 4) Pregnant or breast-feeding woman 5) A patient who has not provided written informed consent to participate in this study. 6) In certain circumstances that the researchers determined it was not suitable for the research

Design outcomes

Primary

Measure	Time frame
painfulness of different concentration of iodine solution	—

Countries

Japan

Contacts

Public ContactTatsuhiro Gotoda

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Gastroenterology and Hepatology

nkjbm234@yahoo.co.jp086-235-7218

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026