Percutaneous periarticular analgesic injection at one day after simultaneous bilateral total knee arthroplasty as a component of multimodal pain management: a randomized control trial

Percutaneous periarticular analgesic injection at one day after simultaneous bilateral total knee arthroplasty as a component of multimodal pain management: a randomized control trial - Percutaneous periarticular analgesic injection at one day after simultaneous bilateral total knee arthroplasty as a component of multimodal pain management: a randomized control trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029759

Enrollment

Registered

2017-11-01

Start date

2017-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Avascular necrosis of femoral condyle, Rheumatoid arthritis

Interventions

Percutaneous periarticular analgesic injection including methylprednisolone 80 mg [2 mL], ropivacaine 150 mg [20 mL], and epinephrine 0.2 mg [0.2 mL] at one day after simultaneous bilateral total knee

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for simultaneous bilateral total knee arthroplasty

Exclusion criteria

Exclusion criteria: Patients scheduled for unilateral total knee arthroplasty. Patients scheduled for total knee arthroplasty combined with implant removal. Patients who had allergy or intolerance to one of the study drugs. Patients who had poorly controlled diabetic mellitus.

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale for postoperative pain at rest measured at 12:00 and 20:00 of one day after surgery, and 6:00, 12:00, and 20:00 of two to five days after surgery.	—

Secondary

Measure	Time frame
Complication Visual Analogue Scale during activity (measured at one to five days after surgery) Range of knee movement (measured at one to five days after surgery)	—

Countries

Japan

Contacts

Public ContactTakuya Iseki

Nekoyama Miyao Hospital Orthopaedic Surgery

takuyaiseki@gmail.com+81252822323

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026