esophageal cancer
Conditions
Interventions
PDD
Sponsors
Nagoya City University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The patient of recurrent esopphageal cacner after CRT who will be trated by Photodynamic therapy(PDT) with Talaporfin. Local failure after CRT or RT:more than 50Gy 2.histologically proven local failure 3.either not candidates for salvage surgery or having a physical status that would make the surgery intolerable 4.lesions limited to within the muscularis propria 5.age more than 20 years old 6.the patient who has no disturbance in liver and kidney. 7.provision of written informed consent
Exclusion criteria
Exclusion criteria: 1. the patinet who can not be inserted endoscope 2. with malignant hypertension, conjestive heart failure, liver dysfunction, myocardil infarction within 3 months, endostage of liver cirrhosis, poor controled DM, severe lung fibrosis, active pneumonitis 3. with active infection 4. inability to comply the sun shade restrictions 5. porphyria 6. severe psychosomatic disturbance 7. allergy against Talaporfin 8. for women, pregnancy or lactation, or unwillingness to use contraception 9. T3 or T4 10. larger than 3cm in diameter 11. half the circumference of the lumen or less 12. invasion to the cervical esophagus 13. patients who judged by the investigator that enrollment was inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety and efficacy of PDD | — |
Countries
Japan
Contacts
Public ContactHiromi Kataoka
Division of Gastroenterology Division of Gastroenterology
Outcome results
None listed