atrial tachyarrhythmia in patients with reduced ejection fraction
Conditions
Interventions
A bisoprolol patch (4 mg) was attached.
Sponsors
Kokura Memorial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: *Patients with sustained atrial fibrillation or flutter treated with continuous infusion of landiolol. *Patients diagnosed with hypertension. *Patients without increasing inotropic agent or oxygen administration within 2 hours before switching therapy. *Patients of 20 years of age or older.
Exclusion criteria
Exclusion criteria: *Patients with an left ventricular ejection fraction of 25-50%. *Patients with systolic blood pressure 90 mmHg or less. *Patients with severe aortic valve stenosis or severe mitral valve stenosis. *Patients with contraindication to beta-blockers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Incidence of adverse event (death, lethal arrhythmia(ventricular tachycardia. ventricular fibrillation), prolongation of hospitalization, and complicaton that leaves sequelae) during the switching therapy. 2)Success rate of the switching therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)The change of blood pressure and heart rate after switching therapy in 2 hours, 12 hours, 24 hours, and 48 hours. 2)The change of blood pressure and heart rate after landiolol administration in 2 hours and 24 hours. | — |
Countries
Japan
Contacts
Public ContactMasato Fukunaga
Kokura Memorial Hospital Department of Cardiology
Outcome results
None listed