depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The adult that the criteria for selection of the depression group meet diagnostic criteria of the depression. The adult that the criteria for selection of the control group have not received a diagnosis of past depression and are less than six points in less than seven points or QIDS-SR-J in HAM-D.
Exclusion criteria
Exclusion criteria: 1.Affected with inflammatory diseases, endocrine diseases, metabolic diseases and severe periodontal diseases. 2.Taken antiallergic drugs, steroid, or immunosuppressive drugs within one month. 3.Affected some brain tissue characteristics obstacles. 4.The past of psychogenic mental disorderd except the depression or endogenous mental disorders and organic mental disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using HAM-D, MADRS, QIDS-SR-J, we score a depression symptom and evaluate association with cytokine density in saliva. | — |
Secondary
| Measure | Time frame |
|---|---|
| Checking psychological stress(K10), the sleep situation(Athens sleeplessness standard)and a personality test(TCI)as well as a depression symptom. | — |
Countries
Japan
Contacts
Shinshu University School of Medicine Department of Psychiatry