Conparative study of usefulness LOQOA tape and existing treatment that is combination of a patch and an oral medication of NSAIDs for osteoarhthritis of the knee

Conparative study of usefulness LOQOA tape and existing treatment that is combination of a patch and an oral medication of NSAIDs for osteoarhthritis of the knee - The analysis of usefulness of LOQOA tape for osteoarthritis of the knee

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029709

Enrollment

216

Registered

2017-11-01

Start date

2017-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis of the knee

Interventions

LOQOA tape is put for four weeks. NSAIDs are administered in addition to putting existing poultices for four weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with the knee to be evaluated at KL classification grade 2-3 2.Patients receiving no treatment for gonarthrosis to be evaluated within 14 days before starting the study (although treatment by taking medicine only when necessary will be allowed) 3.Patients with a standing VAS of 40 mm or higher at the knee to be evaluated when starting the study 4.Patients with no pain symptom on the other (non-evaluated) knee which would affect the evaluation 5.Patients who can receive and understand explanation on the study, and give a written consent by his/her own previously, upon participating the study

Exclusion criteria

Exclusion criteria: 1.Patients who have received joint replacement or highly restricted range of motion (extension/flex) on the knee to be evaluated 2.Patients with other knee pain diseases, diseases impairing ADL, neuropsychiatric diseases, dementia, severe hypertension, peptic ulcer, serious diseases, or skin diseases 3.Patients with a history of dermatitis requiring treatment with patches; 4.Patients with a history of allergy to NSAIDs 5.Patients who have or have had aspirin asthma (asthma attack induced by NSAIDs, etc) 6.Women who are pregnant or possibly pregnant, nursing, or planning to be pregnant, or men who wish his partner to be pregnant, during the study period 7.Other patients applicable to contraindication according to the current product labelling of the study drug.

Design outcomes

Primary

Measure	Time frame
The amount of change in Visual Analog Scale (VAS) after 4 weekes treatment	—

Secondary

Measure	Time frame
The amount of change in Visual Analog Scale (VAS) after 2 weekes treatment The amount of change in Knee Injury and Osteoarthritis Outcome Score (KOOS), JOA score and 2-step test after 2 and 4 weekes treatment The amount of change in Locomo 25 and EQ-5D after 4 weekes treatment	—

Countries

Japan

Contacts

Public ContactShizuka Sasaki

Hirosaki University Graduate School of Medicine Department of Orthopaedic Surgery

shizuka@hirosaki-u.ac.jp0172-39-5083

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026