Healthy adult
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)Japanese (2)Female (3)Age:20-24, Healthy person (At obtaining informed consent) (4)Persons giving written informed consent
Exclusion criteria
Exclusion criteria: (1) Subjects who are sensitive to scent and may cause indefinite complaints or asthma. (2) Subjects who cause skin allergy symptoms (rash, redness, itching etc) by medicine or cosmetics and those with cutaneous hypersensitivity. (3) Subjects who have diseases related to blood circulation disorder. (4) Subjects with a declining thermal sensation or those with excessive sensitivity. (5) Subjects who use topical cream on their forearms. (6) Subjects who have skin symptoms around the site of observation (forearm) that affect the evaluation. For example, scratches, pimples, etc. (7) Subjects who currently go to dermatology office. (8) Subjects who are pregnant, may be pregnant in near future, or are breast-feeding. (9) Subjects who participate in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cold sensation threshold change within 10 minutes after application of aroma components. | — |
Secondary
| Measure | Time frame |
|---|---|
| The probe temperatures and heats flux when the subject feels cold. | — |
Countries
Japan
Contacts
Industrial Research Institute of Shizuoka Prefecture Food Science and Technology