Comparison of an effect of the secondgeneration antihistamines with deiffenrent configuration for Japanese cedar pollinosis (the randomized, placebo controled, double blind study using an environmental challrenge chamber)

Comparison of an effect of the secondgeneration antihistamines with deiffenrent configuration for Japanese cedar pollinosis (the randomized, placebo controled, double blind study using an environmental challrenge chamber) - Comparison of an effect of the antihistaminesfor Japanese cedar pollinosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029653

Enrollment

Registered

2017-10-22

Start date

2017-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

The group which took desloratadine (5mg)on the day before of pollen exposition The group which took levocetirizine (5mg) on the day before of pollen exposition The group which took placebo on the day

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who have medical history of cedar pollinosis for more than 2 years. 2)Patients who do not have nasal symtoms induced by any allergen and requier any drug treatment out of Japanese cedar pollen scattering season. 3)Positive specific IgE to cedar pollen allergen(>=class2) 4)Patients who develop more tha derate symptoms by a pollen exposure for 3 hours.

Exclusion criteria

Exclusion criteria: 1) Drug allergy for antihistaines including intervention medicines 2) Patinets with allergic rhinitis to require treatment in non-scattering period of Japanese cedar pollen 3) Patients with nasal disease that affects the evaluation of the study 4) Severe respiratory disease, heart disease, liver disease, kidney disease, diabetes, autoimmune disease 5) Pregnant women and those at risk of pregnancy 6) Women who are planning pregnancy 7) Lactating woman 8) Patients treated with anti-allergic drugs within 2 week of screening 9) The patients who the doctor judged inappropriate for the study

Design outcomes

Primary

Measure	Time frame
Total nasal symptom score when Japanese cedar pollen exposition was performed for 3 hours in the environmental challrenge chamber	—

Countries

Japan

Contacts

Public ContactYonekura Syuji

Chiba University Graduate School Department of Otorhinolaryngology

syonekura@faculty.chiba-u.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026