Healthy volunteer, 22q11.2 deletion syndrome.
Conditions
Sponsors
National Institute of Radiological Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: I. Patients 20 y.o.<=Age<=55 y.o. patients with 22q11.2 deletion syndrome. II.Healthy volunteers 20 y.o.<=Age<=55 y.o., normal subjects
Exclusion criteria
Exclusion criteria: I. Patients 1. Subjects with any organic brain disorder 2. Subjects with a severe physical complication 3. Subjects who has been taking any dopamine blocker. 4. Subjects who currently smokes 5. Subjects with metallic medical device in the body 6. Subjects with tattoo 7. Subjects with severe claustrophobia 8. Subjects who tends to suicide 9. Pregnant women 10. Subjects who was considered to be inappropriate to participate in the study II. Healthy volunteers 1. Subjects with any psychiatric disorder 2. Subjects with any organic brain disorder 3. Subjects with severe physical complication 4. Subjects who has been taking any dopamine blocker. 5. Subjects who currently smokes 6. Subjects with metallic medical device in the body 7. Subjects with tattoo 8. Subjects with severe claustrophobia 9. Pregnant women 10. Subjects who has participated in other study in recent 6 months. 11. Subjects who was considered to be inappropriate to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference of cerebral dopamine and GABA function between normal controls and patients with 22q11.2 deletion syndrome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlations between cerebral dopamine and GABA function and various clinical scales | — |
Countries
Japan
Contacts
Public ContactKeisuke Takahata
National Institute of Radiological Sciences Department of Functional Brain Imaging Research
Outcome results
None listed