Healthy adults
Conditions
Interventions
Subjects take 200mL test food every morning in daily life for 3 weeks.
Subjects take 200mL placebo every morning in daily life for 3 weeks.
Sponsors
Kyodo Milk Industry Co. Ltd. Research Laboratories
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Healthy adults 2.Subjects who feel eye dryness
Exclusion criteria
Exclusion criteria: 1. Subjects under treatment of eyes 2. Subjects who operated or plan an operation for eyes within three months of screening test 3. Subjects who have serious or progressive illness and symptom 4. Subjects who routinely take pharmaceutical, quasi drug or health food, which may influence the result of this trial (including foods containing oligosaccharide, dietary fiber, hydrogen water and supplements that produce hydrogen gas) 5. Subjects who can avoid the intake of milk and dairy products except test food from screening examination to three weeks later 6. Subjects who have food allergies or drug allergies 7. Subjects with serious lactose intolerance (diarrhea) 8. Subjects who have serious constipation which need to take cathartic drugs and laxative products 9. Subjects under treatment of dry eye 10. Subjects who were enrolled in other trails within one month of screening test 11. Female Subjects who are or might become pregnant 12. Subjects who have history of serious hepatic disorder, renal damage, or myocardial infarction 13. Subjects who have been receiving drug treatment 14. Subjects with severe anemia 15. Inappropriate cases evaluated by doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BUT, Schirmer's test, Questionnaire about ocular symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal microbiota, breath hydrogen concentration, oxidative-stress marker in tear, and questionnaire | — |
Countries
Japan
Contacts
Public ContactYoshitada Hira
imeQ CO. Ltd. CRO division
Outcome results
None listed