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Investigation for clinical factors contributing to accelerated long-term forgetting in epilepsy patients

Investigation for clinical factors contributing to accelerated long-term forgetting in epilepsy patients - Contributing factors for accelerated long-term forgetting in epilepsy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000029570
Enrollment
155
Registered
2017-10-26
Start date
2017-09-26
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Localization Related Epilepsy

Interventions

Neuropsychological exams(day1 &amp
day7) Brain MRI Sleep EEG

Sponsors

Department of Neurology, Neurological Institute, Graduate School of Medicine, Kyushu University
Lead Sponsor
Fukuoka Sanno Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with clinically diagnosed localization related epilepsy 2. Patients are evaluated by board certified epileptologists. Localization related epilepsy is defined as follows; (A) at least two unprovoked seizures occurring greater than 24 hours apart (B) localization is evidenced by at least one of the following examinations; EEG recording, MRI, FDG-PET, SPECT or MEG (C) ictal semiology is compatible to the lesions detected by examinations 3. Fluent in written and spoken Japanese

Exclusion criteria

Exclusion criteria: 1. Estimated full scale IQ <70 2. Suspected aphasia with a screening test 3. History of epilepsy surgery 4. Neurological and psychiatric comorbidities 5. Any contraindications to MRI 6. History of residency in specific cities(Yanagawa city, Yukuhashi city and Beppu city) where movies for original neuropsychological examination were filmed

Design outcomes

Primary

MeasureTime frame
The relationship between ALF and interictal epileptic discharges(IEDs) in non-REM sleep, or temporal lobe lesions in patients with temporal lobe epilepsy

Secondary

MeasureTime frame
Prevalence of ALF in temporal lobe epilepsy and extra-temporal lobe epilepsy

Countries

Japan

Contacts

Public ContactTaira Uehara

Graduate School of Medicine, Kyushu University Department of Clinical Neurophysiology, Neurological Institute

tuehara@neuro.med.kyushu-u.ac.jp092-642-5340

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026