A randomized controlled phase III study comparing circular stapler vs modified Collard technique as esophagogastric anastomosis after esophagectomy for thoracic esophageal cancer

A randomized controlled phase III study comparing circular stapler vs modified Collard technique as esophagogastric anastomosis after esophagectomy for thoracic esophageal cancer - Comparision of esophagogastric anastomosis after esophagectomy for thoracic esophageal cancer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029561

Enrollment

100

Registered

2017-10-16

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic esophageal cancer

Interventions

anastomosis by circular stapler modified Collard technique by linear stapler

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)thoracic esophageal cancer without infiltration to cervical esophagus 2)radical esophagectomy with lympha node dissection 3)gastric conduit reconstruction through posterior mediastinal route or retrosternal route 4)cervical anastmosis 5)ECOG Performance status 0 to 1 6)sufficient function of important organs 7)written informed consent

Exclusion criteria

Exclusion criteria: 1)Salvage surgery 2)Patients performed preoperative chemoradiotherapy 3)severe complications 4)Patients judged inappropriate for the study by the physicians

Design outcomes

Primary

Measure	Time frame
Incidence of anastomotic stricture	—

Secondary

Measure	Time frame
Incidence of anastomotic leakage Incidence of postoperative complication Time of anastomosis QOL	—

Countries

Japan

Contacts

Public ContactTakahiro Hosoi

Aichi Cancer Center Hospital Department of Gastroenterological Surgery

thosoi@aichi-cc.jp052-762-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026