Feasibility study of surgical resection after chemoradiotherapy for locally advanced unresectable pancreatic cancer with major arterial invasion

Feasibility study of surgical resection after chemoradiotherapy for locally advanced unresectable pancreatic cancer with major arterial invasion - Feasibility study of surgical resection after chemoradiotherapy for locally advanced unresectable pancreatic cancer with major arterial invasion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000029501

Enrollment

100

Registered

2017-10-16

Start date

2014-09-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oancreatic cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Cases in which pancreatic cancer has been confirmed from image findings (As far as possible, histology examination / cytodiagnosis is performed to confirm that it is an adenocarcinoma) 2) Patients with locally advanced unresectable pancreatic cancer without distant metastasis 3) Patients whose age is under 80 at the time of consent acquisition 4) Patients with ECOG Performance Status (PS) of 0 or 1 5) Patients whose main organ function is adequately maintained 6) After receiving sufficient explanation for the participation of this study, patients who gained written consent by the patient's free will with sufficient understanding

Exclusion criteria

Exclusion criteria: 1) Patients with distant metastasis 2) Patients with obvious pulmonary fibrosis or interstitial pneumonia (confirmed by chest X-ray) 3) Patients with severe infection complications 4) Patients with difficult heart failure despite treatment, angina pectoris, arrhythmias and myocardial infarction within 6 months after onset 5) diabetic patients who are difficult to control 6) Pregnant women, patients who are lactating or are likely or willing to become pregnant 7) Patients with severe drug allergy 8) Patients with active double cancer 9) Cases showing diarrhea (watery stool) 10) Pleural effusion requiring treatment, ascites retention cases requiring treatment, cases with image pericardial effusion 11) Patients with other serious complications 12) Others, examination responsibility (shared) Patients judged unsuitable by the doctor as subjects

Design outcomes

Primary

Measure	Time frame
Treatment completion ratio	—

Secondary

Measure	Time frame
safety(mobidity, mortality) residual tumor Histological treatment effect Overall survival Relapse-free survival Recurrence form	—

Countries

Japan

Contacts

Public ContactAmano Ryosuke

Osaka City University Graduate School of Medicine Department of Surgical Oncology

ramano@med.osaka-cu.ac.jp06-6645-3838

Outcome results