A prospective study comparing the effect of recombinant human chorionic gonadtropin (r-hCG) versus urine-derived hCG (u-hCG) on oocyte maturation, embryo development, and pregnancy outcome in assisted reproductive technology (ART) cycles

A prospective study comparing the effect of recombinant human chorionic gonadtropin (r-hCG) versus urine-derived hCG (u-hCG) on oocyte maturation, embryo development, and pregnancy outcome in assisted reproductive technology (ART) cycles - Recombinant human chorionic gonadtropin (r-hCG) versus urine-derived hCG (u-hCG)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029446

Enrollment

100

Registered

2017-10-06

Start date

2017-10-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility and subfertility

Interventions

Recombinant human chorionic gonadtropin(r-hCG)250 microgram injection Urine-derived hCG (u-hCG) 10000IU injection

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Infertile/subfertile women undergoing assisted reproductive technology (ART) cycles

Exclusion criteria

Exclusion criteria: Patients who have a history of allergy and adverse effects to the hCG agents

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate	—

Secondary

Measure	Time frame
Oocyte retrieval counts, mature oocyte rate, fertilization rate, and blastocyst rate	—

Countries

Japan

Contacts

Public ContactKotaro Kitaya

Reproduction Clinic Osaka IVF Center

kitaya@koto.kpu-m.ac.jp0661363344

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026