Oral health
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Aged from 30 to 64 years old
Exclusion criteria
Exclusion criteria: 1) Subjects who have oral disease 2) Subjects who participated in other clinical studies in the past 1 month 3) Subjects who had treatment with antibiotics in the past 1 month, or ones who are expected to have treatment with antibiotics 4) Subjects with milk allergy 5) Subjects in pregnancy or breast-feeding 6) Subjects who have a history of serious disorders in liver, kidney, heart, lung, gastro-intestine, blood, endocrine system, or metabolic system etc. 7) Subjects who are judged inappropriate to this trial by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral condition (GI, PLI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary hemoglobin level, Number of periodontopathic bacteria and total bacteria, Dental health-related quality of life, Experience effects, Salivary multi-test system, Infectious diseases | — |
Countries
Japan
Contacts
Matsumoto Dental University Department of Oral Microbiology