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Exploratory study on biomaker for early detection of glaucoma using MRI

Exploratory study on biomaker for early detection of glaucoma using MRI - Early detection of glaucoma using MRI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000029385
Enrollment
10
Registered
2017-10-10
Start date
2017-10-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

MRI measurement Once

Sponsors

Hamamatsu University School of Medicine
Lead Sponsor
Hamamatsu Pharma Research
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patient diagnosed with glaucoma of 20 years or older (primary open angle glaucoma and normal tension glaucoma) 2. Written consent by themselves is given before screening. 3. Written consent by themselves is given for using the data of patient background and image for the research 4. Patient who has left /right difference of visual field defect or retinal nerve fiber layer thickness around the optic disc

Exclusion criteria

Exclusion criteria: 1. Patient who is judged inappropriate by an investigator. 2. Patient who disagrees to the study 3. Patient to be taken MRI difficultly (patient who cannot understand instructions or dementia patients) 4. Patient who inappropriate for MRI (MR noncompliant electronic products and metal fixtures, surgical devices such as metal coils and clips, medical devices such as non-MR compliant cardiac pacemakers, claustrophobia, tattooing, wearing unremovable metal products in the body)

Design outcomes

Primary

MeasureTime frame
Relationship between fractional anisotropy value, retinal nerve fiber thickness and intraocular pressure

Secondary

MeasureTime frame
Relationship between fractional anisotropy value, retinal nerve fiber thickness, intraocular pressure and visual field loss

Countries

Japan

Contacts

Public ContactKazuo Umemura

Hamamatsu University School of Medicine Pharmacology

umemura@hama-med.ac.jp053-435-2269

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026