Effect of probiotics supplementation on improving cognitive function Mild cognitive impairment (MCI)

Effect of probiotics supplementation on improving cognitive function Mild cognitive impairment (MCI) - probiotics and MCI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029340

Enrollment

120

Registered

2017-10-01

Start date

2017-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MCI (Mild Cognitive Impairment)

Interventions

Intake of 2 sachets containing probiotics per day for 24 weeks Intake of 2 placebo sachets per day for 24 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Subjects whose TDAS score is 7 to 13. (2) Those who can understand the purpose and the contents of this study, and can agree with participation.

Exclusion criteria

Exclusion criteria: (1) subjects who are diagnosed as dementia (2) subjects who are stroke patient or have medical history of stroke. (3) subjects who are apnea syndrome patient or have medical history of apnea syndrome. (4) subjects who regularly use medicine or supplement which affect gut-microbiota. (5) subjects with severe disease or medical history of severe disease. (6) Subjects who have participated in other clinical tests within the past three months (7)Subjects who were judged inadequate by investigator for other reasons

Design outcomes

Primary

Measure	Time frame
TDAS(Touch Panel Type Dementia Assessment Scale), Digit Symbol substitution Test	—

Countries

Japan

Contacts

Public ContactTaeko Shimoda

Nara Women's University Faculty of human life and environment Department of food science and nutrition

t-shimoda@cc.nara-wu.ac.jp0742-20-3893

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026