metabolic syndrome
Conditions
Interventions
Drink EH water daily 350 mL 3 times per day for 3 months.
Drink Placebo water daily 350 mL 3 times per day for 3 months.
Sponsors
Department of Preventive Medicine,Kochi University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Persons who are 30 years of age or older who have a resident card and residence in Susaki City and who can install a hydrogen water conditioner (test water conditioner) 2.One who was diagnosed as either 1) or 2) 1) Metabolic syndrome group (from the examination meeting of the Ministry of Health, Labor and Welfare Study meeting) Abdominal girth (male 85 cm or more, female 90 cm or more) plus two or more of the following items A: sugar metabolism (fasting blood glucose 110 mg / dL or more) b: Lipid (neutral fat 150 mg / dL or more or HDL-C 40 mg / dL or less) C: Blood pressure (at least 130 mmHg in systole and / or at least 85 mmHg in diastole) If you are receiving medication for high TG, low HDL-C, hypertension, diabetes, each item To 2) Metabolic Syndrome Preliminary Group (From the results of the study meeting of the Ministry of Health, Labor and Welfare) D: Abdominal girth (male 85 cm or more, female 90 cm or more) Persons whose sugar metabolism, lipid, blood pressure abnormality is up to one item E: Abdominal circumference is not more than the reference value reference value, but those who have BMI 25 or more and have one or more of the above risks Include in each item if you are receiving medication for high TG, low HDL-C, high blood pressure, diabetes.
Exclusion criteria
Exclusion criteria: 1.Person who has judged that doctor is ineligible for participation 1) Heart disease Persons with chronic kidney disease 2) A person with a disease accompanied by weight loss (thyroid hyperthyroidism etc.) 3) There are severe diseases or malignant tumors etc. Person who installed a hydrogen water server 3 Person who is not gaining consent Rationale For setting 1, consideration is given to the safety of the research subjects For. 3) Malignant tumor: When five years have elapsed after completion of recovery, it can be incorporated. 2 In order to influence the main evaluation items.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changing abdominal Circumstance from baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Changes from baseline in stress markers Urinary 8-OHdG, urinary 8-isoprastane, urinary nitrotyrosine 2.Changes from baseline in metabolic syndrome evaluation items Fasting blood sugar, HbA1C, T-C, TG, HDL-C, blood pressure, weight 3.Comparison of nutritional calculation results from FFQ (Food Intake Survey) 4.Effect of test water consumption and hydrogen concentration on evaluation items 5.Presence or absence of adverse events (type, severity, safety level, frequency of occurrence) and frequency of expression) | — |
Countries
Japan
Contacts
Public ContactRyoji Hirota
Kochi University Department of Preventive Medicine
Outcome results
None listed