Single-arm feasibility study of laparoscopic distal gastrectomy for advanced gastric cancer to verify the safety of proximal margins

Single-arm feasibility study of laparoscopic distal gastrectomy for advanced gastric cancer to verify the safety of proximal margins - Single-arm feasibility study of laparoscopic distal gastrectomy for advanced gastric cancer to verify the safety of proximal margins

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029317

Enrollment

130

Registered

2017-10-01

Start date

2017-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Perform laparoscopic distal gastrectomy for patients diagnosed as cT1N2-3, cT2N0-3, cT3N0, or cT4aN0 gastric cancer.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) The cancer is histologically proven adenocarcinoma of the stomach. 2) The cancer has been diagnosed as clinical T1N2-3, T2N0-3, T3N0, T4aN0, and cM0 with no bulky metastatic lymph nodes. 3) The patient is 20 years of age or older. 4) The patient has an Eastern Cooperative Oncology Group performance status of 0 to 2. 5) The patient has no history of treatment for gastric cancer. 6) The patient has a body mass index of less than 35 kg/m2. 7) Written informed consent is provided.

Exclusion criteria

Exclusion criteria: 1) Patients with synchronous double cancer, metachronous double cancer (within 5 years) (except carcinoma in situ). 2) Patients with cT4b, cM1 gastric cancer 3) Patients who went under preoperative treatment for gastric cancer (except staging laparoscopy). 4) Patients with possibility of pregnancy. 5) Patients with mental disorder who are difficult to participate in the study. 6) Patients who are recieving steroid therapy. 7) Patients with viral, bacterial, and fungal infections who requires medical treatment. 8) Patients with poorly controlled diabetes. 9) Patients with unstable angina or myocardial infarction 10) Patients with respiratory disorder who requires oxygen inhalation.

Design outcomes

Primary

Measure	Time frame
Proximal margins	—

Countries

Japan

Contacts

Public ContactRie Makuuchi

Cancer Institute Hospital, Japanese Foundation for Cancer Research Department Gastroenterological Surgery

rie.makuuchi@jfcr.or.jp03-3520-0111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026