Feasibility study of risk reducing mastectomy for women with BRCA1/2 mutations.

Feasibility study of risk reducing mastectomy for women with BRCA1/2 mutations. - Feasibility study of risk reducing mastectomy for women with BRCA1/2 mutations.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029303

Enrollment

Registered

2017-09-27

Start date

2017-08-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hereditary Breast and Ovarian Cancer

Interventions

Risk reducing mastectomy

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: females 20 years or older after receiving genetic counseling in our institution with BRCA1 or 2 mutation without recurrence and distant metastasis desire for risk reducing mastectomy ECOG performance status 0

Exclusion criteria

Exclusion criteria: with other active primary cancer inappropriate mental condition pregnant or nursing severe infection physician judged in appropriateness

Design outcomes

Primary

Measure	Time frame
Adverse events within 1 year aftr surgery	—

Secondary

Measure	Time frame
the rate of occult cancer the rate of locoregional recurrence Adverse events within 5 year aftr surgery	—

Countries

Japan

Contacts

Public ContactAkiyo Yoshimura

Aichi Cancer Center Hospital, Nagoya, Japan Department of Breast Oncology

akiyo@aichi-cc.jp052-762-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026